6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one
| Ngā āhua matū | 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one he wai mārama, kore tae, he kōwhai mārama rānei, kāore e wairewa i te wai, engari e wairewa ana i te CHCl3, me whakatio te wāhi rokiroki, me wehe atu i ngā waikura, i ngā matū e taea te kai, kia matara atu i te ahi, i te pūtake wera rānei. | |
| Ngā tono | 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-onehe takawaenga o Alectinib, he aukati lymphoma kinase (ALK) anaplastic tino whiriwhiri, kaha hoki, ka taea te aukati i te ira whakarerekē ātete gatekeeper, ka hua ake ai te whakaiti i te tipu pūtau. | |
| Āhua ā-tinana | Wai kore tae ki te wai kōwhai | |
| Te roa o te oranga | E ai ki ō mātou wheako, ka taea te rongoa i te hua mō te 12marama mai i te rā tuku mēnā ka rongoatia ki roto i ngā ipu hiri pūmau, ka tiakina mai i te mārama me te wera, ā, ka rongoatia ki ngā pāmahana i waenga i te 5 -30°C. | |
| Tngā āhuatanga noa
| Te Pūtake Kohua | 354.7±42.0 °C i te 760 mmHg |
| Pūwāhi Ngaro | 168.3±27.9 °C | |
| Papatipu Tika | 282.025543 | |
| PSA | 26.30000 | |
| TakiuruP | 3.25 | |
| Pēhanga Kohu | 0.0±0.8 mmHg i te 25°C | |
| Taupū o te Whakaata | 1.545 | |
| pka | 1.26±0.10 (I matapaetia) | |
| Te wairewatanga o te wai | 50 mg/ml i roto i te CHCl3 | |
Haumaru
I te wā e whakamahi ana koe i tēnei hua, me mātua whai i ngā tohutohu me ngā mōhiohio kei roto i te pepa raraunga haumaru, ā, me whai hoki i ngā tikanga tiaki me ngā tikanga akuaku o te wāhi mahi e tika ana mō te whakamahi i ngā matū.
Tuhipoka
Ko ngā raraunga kei roto i tēnei pukapuka i ahu mai i ō mātou mōhiotanga me ngā wheako o nāianei. I runga i ngā āhuatanga maha ka pā ki te tukatuka me te whakamahinga o tā mātou hua, kāore ēnei raraunga e ārai i ngā kaitukatuka mai i te whakahaere i ā rātou ake rangahau me ngā whakamātautau; kāore hoki ēnei raraunga e kī ana he taurangi mō ētahi āhuatanga, kāore hoki i te tika o te hua mō tētahi kaupapa motuhake. Ko ngā whakaahuatanga, ngā tuhi, ngā whakaahua, ngā raraunga, ngā ōwehenga, ngā taumaha, me ētahi atu mea kua hoatu ki konei ka rerekē pea me te kore he mōhiohio o mua, ā, ehara i te mea ko te kounga kirimana kua whakaaetia o te hua. Ko te kounga kirimana kua whakaaetia o te hua ka puta mai i ngā kōrero i roto i te whakatakotoranga hua anake. Ko te kawenga a te kaiwhiwhi o tā mātou hua kia whakarite kia whaihia ngā mana rangatira me ngā ture me ngā ture o nāianei.
